Cardiovascular Health Clinic Logo

The Unique Risks and Warning Signs of Heart Disease in Women

Sep 22, 2025
Attractive brunette young Asian woman makes a heart gesture with her hands while smiling in front of pink background.

Heart disease is the leading cause of death in women, yet it is often misunderstood, underdiagnosed, or overlooked because symptoms tend to present differently than in men. Beyond traditional risk factors like high blood pressure, diabetes, and smoking, women face unique risks tied to pregnancy, menopause, autoimmune disease, and even cancer treatments, all of which can leave lasting effects on the heart. Moreover, because atypical warning signs such as fatigue, jaw pain, or indigestion are often mistaken for less serious issues, women are more likely to delay care and experience worse outcomes. With proactive monitoring, awareness, and healthy lifestyle changes, however, women can dramatically reduce their risk and protect their heart health.

At CardioVascular Health Clinic, we recognize that heart disease in women requires expertise, innovation, and compassion. Our multidisciplinary team of highly experienced specialists works collaboratively to deliver comprehensive care that addresses the unique ways cardiovascular disease impacts women. With state-of-the-art facilities and access to the most advanced diagnostic tools and treatment methods, we provide precise, effective care tailored to each patient. Above all, our dedication to exceptional patient care ensures that every woman receives the support and guidance she needs for complete heart health.

How Heart Disease Develops in Women

Heart disease is often misunderstood as a men’s health issue, yet it is the leading cause of death for women in the United States, claiming more than 300,000 lives each year, or about one in every five female deaths. Despite this, only half of women recognize it as their greatest health threat. This lack of awareness has serious consequences, as women’s symptoms often appear differently than men’s, making them easier to overlook or misdiagnose.

Heart disease refers to a group of conditions that impair the function of the heart and blood vessels. The most common is coronary artery disease, caused by the buildup of fatty deposits called plaque in the arteries. Over time, this process—known as atherosclerosis—narrows or blocks blood flow to the heart muscle. When a blockage is severe enough, it can trigger a heart attack, medically called a myocardial infarction. 

While this process is similar in both men and women, the way it develops and presents in women often differs, primarily because of:

Loss of hormonal protection after menopause.

Women tend to experience heart disease about five to ten years later in life than men, thanks in part to the protective effect of estrogen. Estrogen helps maintain healthy blood vessels and supports cholesterol balance. But when women reach menopause and estrogen levels decline, that protection is lost. The risk of cardiovascular disease rises significantly, and postmenopausal women quickly catch up to men in terms of heart disease prevalence.

Anatomical and structural differences.

Women generally have smaller coronary arteries, thinner heart walls, and smaller ventricles than men. This means that even partial blockages in the smaller arteries can have major effects on blood flow but may not show up as clearly in diagnostic tests. In addition, women are more likely to develop coronary microvascular disease, which affects the small blood vessels of the heart rather than the large coronary arteries. This type of disease can cause persistent chest discomfort during routine activities and is often harder to detect, leading to delays in diagnosis.

5 Unique Risks for Heart Disease Women Face

While traditional risk factors like high blood pressure, high cholesterol, diabetes, obesity, smoking, and physical inactivity apply to both men and women, they often carry a greater burden in women. For example, women with diabetes are more likely than men with diabetes to develop heart disease, and high blood pressure after pregnancy can be especially dangerous if it goes undetected.

Beyond these well-known risks, here are 5 unique challenges women also face that are related to reproductive health and hormonal changes and can increase the chances of developing CVD:

  1. Pregnancy-related complications such as preeclampsia, gestational diabetes, delivering a low- or high-birth-weight baby, preterm delivery, pre‑ or post‑partum cardiac events notably increase long-term CVD risk. Even though these conditions may resolve after pregnancy, they leave a lasting mark on heart health that can appear decades later.
  1. Early menarche (period before age 11) and early menopause (before 40) elevate risk. The premature loss of estrogen accelerates the processes that contribute to atherosclerosis and high blood pressure.
  1. Polycystic Ovary Syndrome (PCOS), endometriosis, and autoimmune diseases (e.g., lupus, rheumatoid arthritis) are all more prevalent in women and can contribute to hormonal imbalances and inflammation, increasing the risk of CVD..
  1. Depression, psychosocial stress, and low social support double women’s likelihood of depression compared to men and correlate with higher heart disease risk. Stress can drive unhealthy coping behaviors like poor diet, lack of sleep, or smoking, while depression is associated with biological changes in blood pressure and inflammation that can strain the heart. Poor mental and emotional health also increase the risk of developing conditions like emotional stress-triggered heart dysfunction.
  1. Breast cancer treatments like radiation and chemotherapy can scar or stiffen cardiac tissue, increasing later heart risk.

What the Warning Signs of Heart Disease Look Like in Women

The greatest danger of heart disease in women may be that its warning signs are not always obvious. For decades, the classic image of a heart attack has been a man clutching his chest in sudden, crushing pain. While some women do experience that symptom, many do not. Women’s symptoms often deviate from the classic “crushing chest pain” and may be quieter, more scattered, leading to frequent underdiagnosis, misattribution (e.g., to stress or reflux), and delayed treatment. 

Common but subtle symptoms of heart disease in women include:

  • Dull discomfort, pressure, or tightness in the chest, often during routine activity. This discomfort can come and go and may appear during normal activities rather than exertion.
  • Pain in the neck, jaw, throat, upper abdomen, back, arms, or shoulders, which are frequently misinterpreted as indigestion, dental problems, or even muscle strain
  • Unusual fatigue, weakness, or feeling “run-down.” Sudden episodes of fatigue that seem out of proportion to daily activity are also common.
  • Nausea, vomiting, indigestion, or abdominal discomfort.
  • Sleep disturbances, palpitations, anxiety.

Women are also more prone to “silent heart attacks”—events without clear symptoms.

Why These Differences Matter for Women and Heart Disease

When women experience subtle or atypical symptoms such as fatigue, indigestion, or jaw pain, these signs are often dismissed, either by the women themselves or by healthcare providers who mistake them for anxiety, hormonal changes, or gastrointestinal issues. The result is delayed treatment, which can be devastating. Every minute during a heart attack means more heart muscle is lost, and research shows women are more likely than men to die after a heart attack, in part because they arrive at the hospital later and face longer times to diagnosis and intervention.

These disparities are compounded by systemic and cultural factors. Historically, cardiovascular research focused on men, creating diagnostic criteria that failed to reflect how heart disease presents in women, a gap often referred to as the “Yentl Syndrome.” Even with more inclusive research today, the effects of that male-centered model linger. 

At the same time, many women underestimate their own risk, believing cancer is a greater threat, or they delay seeking care because of caregiving responsibilities. Together, these challenges mean women are less likely to recognize heart disease, less likely to be diagnosed promptly, and more likely to experience worse outcomes.

What Women Can Do to Lower or Manage Their Risk of Heart Disease

While heart disease remains the leading cause of death in women, it is also highly preventable. Studies show that with consistent health monitoring and lifestyle changes, women can lower their risk of developing heart disease by as much as 80%. Taking proactive steps to understand and manage individual risk factors is critical, because early action not only prevents heart disease but also reduces the severity of future cardiac events.

Here are 5 things women can do to lower or manage their risk of heart disease.

Know your numbers and risk profile. Keep track of your blood pressure, cholesterol, and blood sugar, especially after pregnancy complications or significant hormonal changes, and be proactive about early signs of high blood pressure and diabetes. Understand your unique risk factors and be clear about them when talking with your provider.

Make healthy improvements to your lifestyle. Aim for at least 150 minutes of moderate-intensity exercise per week and focus on a diet that’s rich in whole grains, vegetables, fruits, fiber, and healthy fats but low in saturated fat, trans fat, processed sugar, and excess sodium. If you smoke, try to quit, and avoid secondhand smoke; women may face higher CVD risks than men from smoking.

Protect your psychosocial and emotional health. Manage stress levels and stay in tune with your mental health, including seeking support or treatment for depression and anxiety.

Pay attention to your reproductive and pregnancy health. If you've experienced preeclampsia, gestational diabetes, preterm delivery, or early menopause, talk with your provider about long-term heart monitoring and preventive steps.

Advocate for yourself. Ask for—don’t wait for—appropriate diagnostic tests, especially if symptoms don’t align with “classic” male patterns. If you feel dismissed, seek a second opinion; you know your body best

CardioVascular Health Clinic: Heart Care You Can Count On

At CardioVascular Health Clinic, we are committed to redefining women’s heart health by addressing the unique ways cardiovascular disease affects them. Our team provides comprehensive diagnostics, preventive care, and personalized treatment plans that look beyond symptoms to the full picture of each woman’s health. By combining advanced medical expertise with compassionate, patient-focused care, we empower women to take control of their heart health and build a future that is not only longer, but stronger and healthier.


Schedule a consultation today at CardioVascular Health Clinic and find out how we can help you achieve your best heart health.

Patient Resources

We’re committed to timely, efficient, and affordable care.
Here is a collection of useful resources our new and existing patients need in one convenient location.
Please let us know if you need additional information or have any questions.

Testimonials

I’m about one month out and things are so much better. At my two week evaluation my symptom score had gone from a 27 to a 7, and I’m sure it’s even better now. That speaks volumes. Now that I’m post recovery, there is no incontinence, I go to the bathroom much less and there are no ED side effects like there are with other procedures. In regard to my quality of life, well, I don’t maintain my life based on my proximity to a bathroom anymore.

-
Blaine P., M.D.
Professional staff working in a beautiful facility with great doctors who sincerely care about their patients. Without Dr. Schmidt's skill, I would have needed heart bypass surgery instead of a stent. Follow-up has been thorough. I can't recommend them highly enough.
-
LeAnn H.

Dr. Jim Melton and all the staff are fantastic. He is an excellent surgeon and his team is GREAT!!!! I just had surgery at the surgery center, I have only great things to say about my experience. Without him I really don't think I would be here to write this. If you’re looking for a good cardiovascular team, they are a 5 star for sure.

-
Susie H.

Dr. Parsons and staff are amazing. He truly listened to me from the consult. Staff showed genuine care for my progress post procedure. I had my follow up appointment today so satisfied with results. Blake made me comfortable from the start. He is an activist for uterine fibroids treatment beyond the standard.

-
Tamara M.

Professional and caring staff. Dr. Smith is very knowledgeable and shows genuine concern for your personal health. I enjoyed the background music in the procedure room, it really adds to the relaxing atmosphere.

-
David L.

Dr. John Schrader is the most personable doctor we know. He stays on top of my dads health care and is genuinely concerned about his health. We never leave his office with questions. He answers them all. Even questions we don’t think of. Always professional but never cold or bad bedside manner. In our opinion he is THE BEST around.
Thank you Dr Schrader.

-
Kathy J.

I came to Dr. Warren by a self referral for mals when it took me 8yrs 50+ doctors and thousands of dollars spent on no answers. My first visit I was scared I was just going to be gaslighted just like the past however I was pleasantly shocked when Dr. Warren immediately believed me. She took the time to review many disk I had brought from past tests. She never once dismissed me and listened to ever word I had to say. She scheduled one last test to confirm the diagnosis then I was scheduled for surgery right away. Surgery was a success and I can’t thank her and her staff enough. Dr. Warren truly saved my life.

-
Angie W.

Dr. Garner literally saved my life 18 months ago and I've followed him to his new practice with Cardiovascular Health. He explains things so clearly, listens and is just a very nice person. His staff is great, too! I highly recommend!

-
D Watts

Some of the nicest staff that I have ever dealt with!! They have been so incredibly awesome to my mom!! Would definitely recommend them to anyone!! Thank you so much for being so great with her!!

-
Christy G.

The staff, the nurses, and Dr. Parsons were all amazing. Everything was simple and went well – very Bravo Zulu (military phrase meaning "well done"). In addition to the great staff at CardioVascular Health Clinic, the facilities were clean and well maintained. I have no complaints about anything. The whole experience was A1. I would recommend Dr. Parsons to anyone. He made a huge impact on my life.

-
John W.

Contact Us Today

MM slash DD slash YYYY
MM slash DD slash YYYY
Address
How did you hear about us?(Required)
protected by reCAPTCHA
Privacy - Terms

hello world!
Copyright © 2025 CardioVascular Health Clinic. All Rights Reserved. Website by Healthcare Success.
crossmenu
Copy link
Powered by Social Snap