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High Blood Pressure vs. High Cholesterol: What’s the Difference and Why It Matters for Your Heart

Jun 04, 2025
Close-up of black stethoscope and blood pressure gauge on peach-colored table.

High blood pressure and high cholesterol are two major risk factors for heart disease. While they affect the body differently, they’re closely connected, and when they occur together, they greatly raise the chances of heart attack, stroke, and other serious conditions. “High blood pressure” refers to the consistently elevated level of force as your blood tries to push through your arteries; “high cholesterol” refers to elevated levels of “bad” (low-density lipoprotein, or LDL) cholesterol in your blood that can clog your arteries.

Heart disease is the leading cause of death in the United States and is responsible for about 1 in every 5 deaths each year. It often develops silently over time, without pain, warning signs, or obvious symptoms, so it’s important to understand what can put you at a higher risk for developing it.

Two of the most common and preventable contributors to heart disease–particularly in Oklahoma–are high blood pressure and high cholesterol. Although these terms are closely related and often used together, they are two different conditions that indicate the health of your heart and blood vessels.

The expert team at CardioVascular Health Clinic offers comprehensive care for patients with high cholesterol and high blood pressure, using a blend of innovative diagnostics and personalized treatments. With a focus on whole-person wellness, our specialists tailor each plan to your unique needs, combining minimally invasive procedures, cutting-edge medications, and preventive care strategies. Our commitment to early detection, precise treatment, and long-term management empowers our patients to better protect their heart health and significantly lower their risk for life-threatening cardiovascular events.

High Blood Pressure: The Basics

High blood pressure, also called hypertension, happens when the force of blood pushing against your artery walls is consistently too high. This puts extra strain on your heart and blood vessels, sort of like water flowing too forcefully through a garden hose.

Your blood pressure reading has two numbers: the top number (systolic) measures pressure when your heart beats, and the bottom number (diastolic) measures pressure when your heart rests between beats. A normal reading is usually around 120/80 mmHg. Anything consistently over 130/80 mmHg is considered high.

According to the Centers for Disease Control and Prevention (CDC), nearly half of U.S. adults — about 48% — have high blood pressure, and many don’t even know it. That’s what makes it so dangerous. Left untreated, it can lead to serious problems like heart attack, stroke, kidney damage, and vision loss.

There’s no single cause of high blood pressure. It can be related to genetics, poor diet, stress, being overweight, lack of exercise, or certain medical conditions. Often, it’s a combination of factors.

High Cholesterol: The Basics

Cholesterol is a waxy, fat-like substance your body needs to build cells and make hormones. It becomes a problem when there’s too much of the “bad” kind — called LDL, or low-density lipoprotein — circulating in your blood.

Too much LDL cholesterol can stick to the walls of your arteries and form plaque, which narrows the space for blood to flow. This condition is called atherosclerosis, and it can increase your risk for heart attacks, strokes, and other serious issues.

There’s also “good” cholesterol — high-density lipoprotein — that helps remove excess LDL from your bloodstream.

High cholesterol often doesn’t cause symptoms, which is why regular blood tests are important. Nearly 35% of U.S. adults have elevated total cholesterol, which is greater than 200 mg/dL. And 10% of U.S. adults have total cholesterol levels of more than 240 mg/dL, putting them at substantial risk for cardiovascular disease.

High levels of cholesterol can have several causes. Some people are genetically predisposed to high cholesterol levels. Others develop it because of lifestyle habits, like a diet high in saturated fats, smoking, or not getting enough physical activity. Age can play a role as well as certain medical conditions, like diabetes or thyroid disorders.

The Differences Between High Blood Pressure and High Cholesterol

It’s easy to confuse high blood pressure and high cholesterol because they both affect your heart and blood vessels and they’re often referred to in conjunction with each other. But they’re actually quite different.

  • High blood pressure is about the force of blood pressing against your arteries.
  • High cholesterol is about the substance — specifically fat — that can clog your arteries.

You can have one condition without the other, or both at the same time. They have different causes, different numbers to watch, and different treatment approaches. But even though they’re separate issues, they often occur together, and that’s where the risk increases.

How High Blood Pressure and High Cholesterol are Connected

High blood pressure and high cholesterol don’t just share risk factors. They also work together to damage your arteries. Here’s how.

High cholesterol can cause high blood pressure.

When you have high cholesterol, plaque can start to build up along your artery walls, narrowing and stiffening the space where blood can flow in a process called atherosclerosis. That narrowing makes it harder for your heart to pump blood effectively, which raises your blood pressure.

High blood pressure can exacerbate high cholesterol.

On the flip side, if you already have high blood pressure, that constant force against your artery walls can cause tiny injuries. Those damaged areas are the perfect spot for cholesterol to settle and form plaque buildup.

In other words, one condition can make the other worse. Together, they create a dangerous cycle that increases your risk for heart disease, stroke, and other cardiovascular complications.

The Impacts of High Blood Pressure and High Cholesterol on Heart Health

The combination of high blood pressure and high cholesterol can put your heart under tremendous strain. Over time, this can:

  • Narrow or block arteries, reducing the oxygen and nutrients your heart and brain receive.
  • Weaken the heart muscle, forcing it to work harder to push blood through tight, stiff arteries.
  • Increase the risk of blood clots, which can cause heart attacks or strokes.
  • Lead to heart failure, a condition where the heart can’t pump blood efficiently.

Most concerning is that both conditions are known as silent killers, because they rarely cause symptoms until serious damage has already been done. That’s why prevention, early detection, and regular monitoring are so important. You don’t want to wait and react only when something feels wrong; you want to protect your heart long before that point.

Managing Both High Blood Pressure and High Cholesterol for Better Heart Health

The good news is that high blood pressure and high cholesterol are both manageable — and often preventable.

Here’s how you can take charge of your heart health, including your blood pressure and your cholesterol levels:

  • Visit your doctor regularly. Annual checkups and routine blood work can help catch problems early.
  • Eat a heart-healthy diet. Choose foods like fruits, vegetables, whole grains, lean proteins, and healthy fats. Cut back on red meat and processed foods.
  • Get moving. Aim for at least 30 minutes of physical activity most days of the week — walking, biking, dancing, or anything that gets your heart pumping.
  • If you smoke, quit. Tobacco use, including smoking, vaping, and chewing tobacco, damages your blood vessels, and can lower your good cholesterol while raising levels of bad cholesterol.
  • Limit the amount of alcohol you drink. Too much alcohol (more than one drink daily for women and two for men) can raise blood pressure and triglycerides.
  • Take your prescribed medication. Your doctor may have prescribed medicine to manage your blood pressure (like ACE inhibitors or beta blockers) or lower your cholesterol (like statins). It’s important to take your medicine as directed by your doctor, even if you feel fine.

Living a healthy lifestyle is not about being perfect; small, sustainable changes really do add up over time and can make a big difference in improving your health.

Take Control of Your High Blood Pressure and High Cholesterol with CardioVascular Health Clinic

High blood pressure and high cholesterol are two of the most common threats to heart health, and they often go hand in hand. While they each affect the body in different ways, combined together, they can have a serious impact on your health. With the right tools, information, and support, however, both conditions can be managed, and by taking steps to care for your heart today, you’re protecting your future.

At CardioVascular Health Clinic, our multidisciplinary team of interventional cardiologists, vascular surgeons, and specialized providers works together to diagnose, treat, and manage chronic conditions like high cholesterol and high blood pressure. Using advanced imaging and diagnostic technologies, we can accurately assess cardiovascular risk and create customized treatment plans that work for your life. With an approach that combines state-of-the-art medical therapies with preventive strategies, we help patients across Oklahoma not only control these conditions but also reduce the risk of heart attack, stroke, and other complications through lifestyle counseling, medication management, and continuous monitoring.If you haven’t had your blood pressure or cholesterol checked recently, it’s time to schedule a visit with your doctor. Reach out to the team at CardioVascular Health Clinic and take the first step toward better health.

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I’m about one month out and things are so much better. At my two week evaluation my symptom score had gone from a 27 to a 7, and I’m sure it’s even better now. That speaks volumes. Now that I’m post recovery, there is no incontinence, I go to the bathroom much less and there are no ED side effects like there are with other procedures. In regard to my quality of life, well, I don’t maintain my life based on my proximity to a bathroom anymore.

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Professional staff working in a beautiful facility with great doctors who sincerely care about their patients. Without Dr. Schmidt's skill, I would have needed heart bypass surgery instead of a stent. Follow-up has been thorough. I can't recommend them highly enough.
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LeAnn H.

Dr. Jim Melton and all the staff are fantastic. He is an excellent surgeon and his team is GREAT!!!! I just had surgery at the surgery center, I have only great things to say about my experience. Without him I really don't think I would be here to write this. If you’re looking for a good cardiovascular team, they are a 5 star for sure.

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Susie H.

Dr. Parsons and staff are amazing. He truly listened to me from the consult. Staff showed genuine care for my progress post procedure. I had my follow up appointment today so satisfied with results. Blake made me comfortable from the start. He is an activist for uterine fibroids treatment beyond the standard.

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Tamara M.

Professional and caring staff. Dr. Smith is very knowledgeable and shows genuine concern for your personal health. I enjoyed the background music in the procedure room, it really adds to the relaxing atmosphere.

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David L.

Dr. John Schrader is the most personable doctor we know. He stays on top of my dads health care and is genuinely concerned about his health. We never leave his office with questions. He answers them all. Even questions we don’t think of. Always professional but never cold or bad bedside manner. In our opinion he is THE BEST around.
Thank you Dr Schrader.

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Kathy J.

I came to Dr. Warren by a self referral for mals when it took me 8yrs 50+ doctors and thousands of dollars spent on no answers. My first visit I was scared I was just going to be gaslighted just like the past however I was pleasantly shocked when Dr. Warren immediately believed me. She took the time to review many disk I had brought from past tests. She never once dismissed me and listened to ever word I had to say. She scheduled one last test to confirm the diagnosis then I was scheduled for surgery right away. Surgery was a success and I can’t thank her and her staff enough. Dr. Warren truly saved my life.

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Angie W.

Dr. Garner literally saved my life 18 months ago and I've followed him to his new practice with Cardiovascular Health. He explains things so clearly, listens and is just a very nice person. His staff is great, too! I highly recommend!

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D Watts

Some of the nicest staff that I have ever dealt with!! They have been so incredibly awesome to my mom!! Would definitely recommend them to anyone!! Thank you so much for being so great with her!!

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Christy G.

The staff, the nurses, and Dr. Parsons were all amazing. Everything was simple and went well – very Bravo Zulu (military phrase meaning "well done"). In addition to the great staff at CardioVascular Health Clinic, the facilities were clean and well maintained. I have no complaints about anything. The whole experience was A1. I would recommend Dr. Parsons to anyone. He made a huge impact on my life.

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